Andrea Cabrera Pastor Andrea Cabrera Pastor
Andrea Cabrera Pastor

Postdoctoral Laboratori de Neurobiologia del Centre d'Investigació Príncep Felip


Currículum i Publicacions Currículum i Publicacions


  • Doctora en Ciències Biològiques. Universitat de València. 


  • Cabrera-Pastor A, Balzano T, Hernández-Rabaza V, Malaguarnera M, Llansola M, Felipo V. Increasing extracellular cGMP in cerebellum in vivo reduces neuroinflammation, GABAergic tone and motor in-coordination in hyperammonemic rats. Brain, Behaviour and Immunity. (2018).
  • Cabrera-Pastor A, Taoro-González L, Cuñat A.N., Canet-López D., Balzano T., Felipo V. Extracellular Cyclic GMP Modulates Membrane Expression of The GluA1 and GluA2 Subunits of AMPA Receptor in Cerebellum: Molecular Mechanisms Involved. Scientific Reports. (2018). 
  •  Cabrera-Pastor A, Taoro-González L, López-Merino E, Celma F, Llansola M, Felipo V. Chronic hyperammonemia alters in opposite ways membrane expression of GluA1 and GluA2 AMPA receptor subunits in cerebellum. Molecular mechanisms involved. Biochim Biophys Acta. (2018). 
  • Gómez-Giménez B, Llansola M, Cabrera-Pastor A, Hernández-Rabaza V, Agustí A, Felipo V. Endosulfan and Cypermethrin Pesticide Mixture Induces Synergistic or Antagonistic Effects on Developmental Exposed Rats Depending on the Analyzed Behavioral or Neurochemical End Points. ACS Chem Neurosci. (2017).
  • Gómez-Giménez B, Felipo V, Cabrera-Pastor A, Agustí A, Hernández-Rabaza V, Llansola M. 


    Developmental Exposure to Pesticides Alters Motor Activity and Coordination in Rats: Sex Differences and Underlying Mechanisms

    Neurotox Res. (2017).
  • Agusti A, Hernández-Rabaza V, Balzano T, Taoro-Gonzalez L, Ibañez-Grau A, Cabrera-Pastor A, Fustero S, Llansola M, Montoliu C, Felipo V. Sildenafil reduces neuroinflammation in cerebellum, restores GABAergic tone, and improves motor in-coordination in rats with hepatic encephalopathy. CNS Neurosci Ther. (2017).
  • Gómez-Giménez B, Llansola M, Hernández-Rabaza V, Cabrera-Pastor A, Malaguarnera M, Agusti A, Felipo V. Sex-dependent effects of developmental exposure to different pesticides on spatial learning. The role of induced neuroinflammation in the hippocampus. Food Chem Toxicol. (2016)
  •  Dadsetan S, Balzano T, Forteza J, Cabrera-Pastor A, Taoro-Gonzalez L, Hernandez-Rabaza V, Gil-Perotín S, Cubas-Núñez L, García-Verdugo JM, Agusti A, Llansola M, Felipo V. Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy. Front Mol Neurosci (2016)
  •  Cabrera-Pastor A, Llansola M, Felipo V. Extracellular Protein Kinase A Modulates Intracellular Calcium/Calmodulin-Dependent Protein Kinase II, Nitric Oxide Synthase, and the Glutamate-Nitric Oxide-cGMP Pathway in Cerebellum. Differential Effects in Hyperammonemia. ACS Chem Neurosci. (2016)
  • Cabrera-Pastor A, Malaguarnera M, Taoro-Gonzalez L, Llansola M, Felipo V. Extracellular cGMP Modulates Learning Biphasically by Modulating Glycine Receptors, CaMKII and Glutamate-Nitric Oxide-cGMP Pathway. Scientific Reports (2016)
  • Dadsetan S, Balzano T, Forteza J, Agusti A, Cabrera-Pastor A, Taoro-Gonzalez L, Hernandez-Rabaza V, Gomez-Gimenez B, ElMlili N, Llansola M, Felipo V. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. J Neuroinflammation (2016)
  • Belghiti M, Agusti A, Hernandez-Rabaza V, Cabrera-Pastor A, Llansola M, Felipo V. Sildenafil Treatment Eliminates Pruritogenesis and Thermal Hyperalgesia in Rats with Portacaval Shunts. Neurochem Res. (2016
  • Cabrera-Pastor A., Hernández-Rabaza V., Taoro-González L., Balzano T., Llansola M., Felipo V. In vivo administration of extracellular cGMP normalizes TNF-a and membrane expression of AMPA receptors in hippocampus and spatial reference memory but not IL-1b, NMDA receptors in membrane and working memory in hyperammonemic ratsBrain, Behaviour and Immunity (2016).

  • Hernández-Rabaza V., Cabrera-Pastor A., Taoro-González L., Gonzalez-Usano A., Agusti A., Balzano T., Llansola M., Felipo V. Neuroinflammation increases GABAergic and impairs cognitive and motor fucntion in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane bt promoting M2 polarization of microglia. Journal of Neuroinflammation (2016).
  •  Hernández-Rabaza V., Cabrera-Pastor A., Taoro-González L., Malaguarnera M., Llansola M., Felipo V. Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning. Reversal by sulforaphane. Journal of Neuroinflammation (2016).
  • Cabrera-Pastor A., Taoro L., Felipo V. Hyperammonemia alters glycinergic neurotransmission and modulation of the glutamate-NO-cGMP pathway by extracellular glycine in cerebellum in vivo. Journal of Neurochemistry (2016).
  • Cabrera-Pastor A., Taoro L., Llansola M., Felipo V. Roles of NMDA receptor and EAAC1 transporter in modulation of extracellular glutamate by low and high affinity AMPA receptors in cerebellum in vivo. Differential alteration in chronic hyperammonemia. ACS Chemical Neuroscience (2015).
  • Hernandez-Rabaza V., Agustí A., Cabrera-Pastor A., Fuster S., Delgado O., Taoro L., Montoliu C., Llansola M., Felipo V. Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy. Underlying mechanisms. Journal of Neuroinflammation (2015) 

  • Agustí A., Llansola M., Hernandez-Rabaza V., Cabrera-Pastor A.Montoliu C., Felipo V. Modulation of GABAA receptors by neurosteroids. A new concept to improve cognitive and motor alterations in hepatic encephalopathy. The journal of steroid biochemistry and molecular biology (2015)
  • Llansola M.,  Montoliu C.,  Agusti A.,  Hernandez-Rabaza V., Cabrera-Pastor A.Malaguarnera M., Gomez-Gimenez B.Orts A. Garcia-Garcia R.,  Balzano T., Taoro L.,  Felipo VTranslational research in hepatic encephalopathy: New diagnostic possibilities and new therapeutic approachesNew Horizons in Translational Medicine (2014)

  • Llansola M.,  Montoliu C.,  Agusti A.,  Hernandez-Rabaza V.,  Cabrera-Pastor A.,  Gomez-Gimenez B.,  Malaguarnera M.,  Dadsetan S.,  Belghiti M.,  Garcia-Garcia R.,  Balzano T., Taoro L.,  Felipo V. Interplay between glutamatergic and gabaergic neurotransmission alterations in cognitive and motor impairment in minimal hepatic encephalopathy. Neurochemistry International (2014)

  • Omar Cauli, Alba González-Usano, Andrea Cabrera-Pastor, Carla Gimenez-Garzó, Pilar López-Larrubia, Amparo Ruiz-Sauri, Vicente Hernández-Rabaza, Malgorzata Duszczyk, Michal Malek, Jerzy W. Lazarewicz, Arturo Carratalá, Amparo Urios, Alfonso Miguel, Isidro Torregrosa, Carmen Carda, Carmina Montoliu and Vicente Felipo. Blocking NMDA receptors delays death in rats with acute liver failure by dual protective mechanisms in kidney and brain. Journal NeuroMolecular Medicine (2013).

  • Llansola M, Ahabrach H, Errami M, Cabrera-Pastor A, Addaoudi K, Felipo V. Imparied release of corticosterone from adrenals contributes to impairment of circadian rhythms of activity in hyperammonemic rats. Archives of biochemistry and biophysics (2013).

  • Llansola M., Montoliu C., Cauli O., Hernández-Rabaza V., Agustí A., Cabrera-Pastor A., Giménez-Garzó C., González-Usano A., Felipo V. Chronic hyperammonemia, glutamatergic neurotransmission and neurological alterations. Metabolic brain disease (2012).
  • Cabrera-Pastor A., Llansola M., Reznikov V., Boix J., Felipo V. Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo. Neurochemistry International (2012)

  • Boix J., Llansola M., Cabrera-Pastor A., Felipo VMetabotropic glutamate receptor 5 modulates the nitric oxide-cGMP pathway in cerebellum in vivo through activation of AMPA receptors. Neurochemistry International (2011).

  •  Iranzo V, Sirera R, Carrato A, Cabrera A, Jantus E, Guijarro R, Sanmartín E, Blasco A, Gil M, Gómez-Aldaraví L, González-Larriba JL, Massuti B, Velasco A, Provencio M, Rossell R, Camps CPhase II clinical trial with gemcitabine and paclitaxel sequential monotherapy as first-line treatment for advanced non-small cell lung cancer. Clinical Translational Oncology (2011).
  • Jantus-Lewintre E, Sirera R, Cabrera A; Blasco A; Caballero A; Iranzo V, Rosell R, Camps C. Analysis of the prognostic value of soluble epidermal growth factor receptor plasma concentration in advanced non-small cell lung cancer patients. Clinical Lung Cancer (2011).
  • Sirera R, Bremnes R.M., Cabrera A, Jantus-Lewintre E, Sanmartín E, Blasco A, Pozo N, Rosell R, Guijarro R, Galbis J, Sánchez J and Camps C. Circulating DNA is a useful prognostic factor in patients with advanced non-small cell lung cancer.  Journal of Thoracic Oncology (2011).

  • Camps C, Jantus-Lewintre E, Cabrera A, Blasco A, Sanmartín E, Gallach S, Caballero C, Pozo N, Rosell R, Guijarro R, Sirera R. The identification of KRAS mutations at codon 12 in plasma DNA is not a prognostic factor in advanced non-small cell lung cancer patients.  Lung Cancer (2010).
  • Sirera R, Gil M, Blasco A, Cabrera A, Safont MJ, Iranzo V, Cayuela D, Rosell R, and Camps C. Retrospective analysis of the prognostic role of p16 protein inactivation in plasma in patients with locally advanced non-small cell lung cancer. Lung Cancer (2008).